In the previously mentioned study by Werner et al., the authors also investigated the association of fecal anti-GP2 and associations with pouchitis.21 Fecal samples were obtained in 11 patients with recurrent, acute pouchitis (patients with episodes of antibiotic-responsive pouchitis with repeated flares up to four times per year), 17 with chronic pouchitis (patients requiring antibiotic or anti-inflammatory therapy for at least four weeks or patients having more than five flares per year), nine with a normal pouch, and five with FAP. The gene discussed is GP2; the disease is pouchitis.