COG2 and heart failure: The LDL-C, troponin I, NT-proBNP, FGF21 levels, LAD, LVEDD, LVESD, and LVESV were higher in the heart failure group than in the no heart failure group, while the HDL-C levels and LVEF were lower than in the no heart failure group (Table 1) (P < 0.05).