MBP and Autoimmunity: In this study DCs specifically pulsed with a peptide (a segment of MBP in which the amino acid lysine in position 91 is replaced by alanine), were injected into the site of spinal cord contusion in rats. This modified peptide (A91) has been shown to cross-react with the original encephalitogenic peptide, activating weak self-reacting T-cell and thereby inducing autoimmunity without the risk of inducing experimental autoimmune encephalomyelitis (EAE), thus a well-regulated primary immune response was created to provide neuroprotection