TNF and rheumatoid arthritis: Table 1 describes in detail patients’ demographic and clinical characteristics. As observed, our population was mostly comprised by young patients, nonsmokers, with extensive colitis (Montreal E3), with a median partial Mayo score of 7.06 and Mayo endoscopic subscore of 3. Five patients had concomitant rheumatoid arthritis. Most patients (64.3%, n = 38) were previously exposed to anti-TNF agents.