TNF and neoplasm: Tconv cells promote tumor control through the stimulation of, among other cells, CD8+ T cells, natural killer (NK) cells, and a broad range of other innate immune cell types. Furthermore, they exert cytotoxic functions that result in the killing of human leukocyte antigen (HLA) class II-expressing tumor cells or they inhibit tumor growth through the secretion of IFNγ and TNF