Activated KCs in NAFLD/NASH patients are F4/80+, CD14+, CD16+ and CD68+ (21, 27, 37–40) and in NAFLD mouse models are F4/80+, CD11blow, CD68+ and Clec4f+ (21, 27, 38). The gene discussed is CLEC4F; the disease is metabolic dysfunction-associated steatohepatitis.