Activated KCs in NAFLD/NASH patients are F4/80+, CD14+, CD16+ and CD68+ (21, 27, 37–40) and in NAFLD mouse models are F4/80+, CD11blow, CD68+ and Clec4f+ (21, 27, 38). Here, CLEC4F is linked to metabolic dysfunction-associated steatotic liver disease.