Interestingly, apart from lymphocyte migration and LPS signaling, several genes related to type I interferon signaling and responses to viral infection were upregulated after GF culture with DAC (APOBEC3C, IFITM1, RSAD2, IFI27, OAS2, MX1, IFI6, ISG15, SAMHD1) (Figure 5C). Here, ISG15 is linked to viral infectious disease.