Collapsin response mediator protein 2 (CRMP2) is a phosphorylation target of GSK3β (Wilson et al., 2014; Zhang and Koch, 2017) that has been implicated in schizophrenia (Zhang et al., 2016), AD (Yang et al., 2017) and depression (Xiang et al., 2020). Here, DPYSL2 is linked to major depressive disorder.