TYR and atopic eczema: Glycyrrhizic acid exhibits anti-inflammatory, immunomodulatory, and antiviral effects.121 It has also been shown to modulate UV light-mediated damage to dermal fibroblasts.122 In a small clinical trial, topical preparations were also shown to improve atopic dermatitis symptoms.123 Glabridin, liquiritin, and isoliquiritin exhibit anti-melanogenic effects through the inhibition of tyrosinase and dispersal of melanin, and this has been demonstrated in preclinical studies.124 High-quality clinical trials remain elusive.