CAV1 and lipodystrophy: Although mutations in CAV1 are mostly associated with a lipodystrophy phenotype, it is worth noting that Berger et al. (Berger et al., 2002) reported a patient with atypical lipodystrophy who also suffered from retinitis pigmentosa, and later Cao et al. (Cao et al., 2008) established a CAV1 truncating mutation as the causative genetic aberration.