PDGFRB and Scleroderma Polymyositis Overlap Syndrome: Vasculopathy in scleromyositis has been shown in the form of capillary dropout and enlargement on light microscopy, abnormal capillary expression of VEGF or PDGFR-β on immunohistochemistry, and basement membrane reduplication with endothelial activation and/or increased numbers of ensheathed pericyte processes on electron microscopy (20, 24, 25, 63).