GBP2 and colitis: In A1-specific markers of astrocyte, H2-D1, H2-T23, GBP2 and CFB mRNA levels were significantly increased by 51.9%, 44.8%, 52.9% and 121.8% (Figures 6A–D), while SerpinG1 was decreased by 24.8% in 2% DSS group compared with Control group (Figure 6E), which indicated the expression of A1-specific markers of astrocyte was elevated in colitis group.