In this research, by analyzing the clinical data of LGG patients in TCGA and combining it with coproptosis, we constructed 5 (GAS5.AS1, MYLK.AS1, AC142472.1, AC011346.1, AL359643.3) cuproptosis-related lncRNAs prognostic models, analyzed and predicted their clinical prognosis, and found the relationship between them and tumor immunity.The discriminability and precision of the developed lncRNA signatures were validated using Kaplan-Meier survival analysis and area under the curve (AUC). Here, MYLK is linked to neoplasm.