In an exploratory analysis, we found that the SUVmax of tumor post-NCIO was significantly associated with tumor size of post-NCIO (Spearman correlation = 0.462, P = 0.001), TC of pre-NCIO was significantly associated with B-cell count of pre-NCIO (Pearson correlation = 0.404, P = 0.033) and NK-cell count of pre-NCIO (Spearman correlation = -0.396, P = 0.041), HDL-C of pre-NCIO had a trend of correlation with CD8+ T-cell rate of pre-NCIO (Spearman correlation = 0.3142, P = 0.070), CEA of pre-NCIO was significantly associated with T count of pre-NCIO (Spearman correlation = -0. This evidence concerns the gene CD8A and neoplasm.