Briefly, for both pCR and MPR, the AUC of SUVmax of tumor post-NCIO was significantly larger than that of PD-L1 expression of pre-NCIO and tumor size of post-NCIO (all P < 0.05); and the AUC of △SUVmax rate of tumor post-NICO was significantly larger than that of PD-L1 expression of pre-NCIO (P < 0.05). This evidence concerns the gene CD274 and neoplasm.