LECT2, RORC, RBP7, ZAP70, HLA−DRB5, and CD8A were protective factors with a hazard ratio (HR)<1, whereas BIRC5, PLXNA1, PGF, and IKBKE were risk factors with HR >1 in patients with HCC (Figure 3A). This evidence concerns the gene IKBKE and hepatocellular carcinoma.