Another 77-year-old woman was also reported as APL with FIP1L1::RARA and the FLT3-ITD, FLT3-D835Y, CEBPA and NPM1 mutations were not detected, PML::RARA, AML1::ETO, and CBFβ::MYH11 fusion genes were negative. The gene discussed is FIP1L1; the disease is acute promyelocytic leukemia.