We found that “stem cells,” “cancer,” “in vitro,” “colorectal cancer,” “model,” “culture,” “differentiation” and “growth” were the most frequently occurring keywords, and “3D culture,” “tumor model,” “beta catenin,” “inflammatory bowel disease,” “small intestine,” “P53” and “cancer metabolism” were the most central keywords. This evidence concerns the gene CTNNB1 and inflammatory bowel disease.