We found that “stem cells,” “cancer,” “in vitro,” “colorectal cancer,” “model,” “culture,” “differentiation” and “growth” were the most frequently occurring keywords, and “3D culture,” “tumor model,” “beta catenin,” “inflammatory bowel disease,” “small intestine,” “P53” and “cancer metabolism” were the most central keywords. The gene discussed is CTNNB1; the disease is colorectal cancer.