reported that PIMREG was related to overall survival (OS) and recurrence-free survival (RFS) of ccRCC and could be used as a biomarker of prognosis, we further verified the biological function of PIMREG in ccRCC through in vitro experiments and analyzed the relationship between PIMREG and immune infiltration and drug resistance (15, 16). Here, PIMREG is linked to nonpapillary renal cell carcinoma.