Histological analysis of brain tumor sections implies a role for angiogenesis and vascular mimicry in GEMM and PDOX tumor sections of SHH and Gp3 MB (39), with an earlier study identifying elevated Vascular endothelial growth factor (VEGF), a principal angiogenic factor, in cell line xenograft Gp3 models and Gp3 MB patients (56). The gene discussed is VEGFA; the disease is brain neoplasm.