These findings are strengthened by the evidence that B cell-specific deletion of Glut1 leads to substantially decreased numbers of peripheral B cells in mice (72) and that Glut1 expression is necessary to maintain elevated glucose metabolism and to promote cell survival of human MM and B cell acute lymphoblastic leukemia (B-ALL) (73, 74). The gene discussed is SLC2A1; the disease is acute lymphoblastic leukemia.