Subsequent studies revealed that deletions and inactivating mutations of TRAF3 are frequently detected in many other types of mature B cell malignancies, including diffuse large B-cell lymphoma (DLBCL), splenic marginal zone lymphoma (MZL), B-cell chronic lymphocytic leukemia (B-CLL), mantle cell lymphoma (MCL), Waldenström’s macroglobulinemia, and Hodgkin lymphoma (HL) (1, 3, 9–11, 30). This evidence concerns the gene TRAF3 and Hodgkins lymphoma.