The high frequency of TRAF3 deletions and inactivating mutations was verified in a larger cohort of patient study by Walker et al., which reported 16.7% genetic alterations of TRAF3 in 463 examined MM patients, including 13% of deep deletions, 3.26% of mutations, and 0.43% of truncations of the TRAF3 gene (26). This evidence concerns the gene TRAF3 and Miyoshi myopathy.