miR-205 enhances inflammatory and stemness properties in stemness-enriched HNSCC cells and promotes tumorigenesis and tumor progression via downregulating COMMD1. COMMD1 downregulation also enhances the activation of NF-κB in HNSCC cells, which in turn promotes the release of inflammatory factors into the tumor microenvironment and further increases miR-205 expression (78). This evidence concerns the gene COMMD1 and neoplasm.