Table 1 showed the baseline characteristics of all subjects. No significant difference was observed in the level of peak high sensitivity cardiac troponin I (hs-cTnI), the pericardial effusion rate, the pleural effusion rate and cardiac symptom rate between rLVEF patients and pLVEF patients. The level of peak N-terminal prohormone of brain natriuretic peptide (NT-proBNP) of rLVEF patients was markedly elevated compared to pLVEF patients (5703.5 [2682.5, 8136.5] pg/ml vs. 1659.5 [492.5, 4574.5] pg/ml, p = 0.024). The gene discussed is NPPB; the disease is Pleural effusion.