MUC16 and ovarian carcinoma: Techniques used to detect CA-125 lack the sensitivity (> 75%) and specificity (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\ge 99.6 \%)$$\end{document}≥99.6%) required to be used in a general-population screening program for detection of ovarian cancer [85, 86].