GH1 and neoplasm: In this study we aimed to characterise transcriptomic patterns of GH-producing PitNETs specifically assessing impact of SSA treatment effects on gene expression on several levels and functional models of GH-producing PitNETs: tumour tissue of patients with and without SSA preoperative treatment, tumour derived pituisphere model and classically used GH3 cell lines treated with SSA.