Consistently, in the present study, we found that IGF1R is co-overexpressed with N-cadherin in GC, and IGF1 level is positively correlated with mesenchymal phenotype markers (including Snail, Twist1, Zeb1, Slug, Vimentin, MYH11, LEF1, and FAP) and negatively correlated with epithelial phenotype marker MUC1 in GC. The gene discussed is CDH2; the disease is gastric cancer.