Consistently, in the present study, we found that IGF1R is co-overexpressed with N-cadherin in GC, and IGF1 level is positively correlated with mesenchymal phenotype markers (including Snail, Twist1, Zeb1, Slug, Vimentin, MYH11, LEF1, and FAP) and negatively correlated with epithelial phenotype marker MUC1 in GC. This evidence concerns the gene IGF1R and gastric cancer.