The cellular actions of BDNF were mediated through tyrosine kinase receptor B (TrkB) and by p75NTR (p75 neurotrophin receptor), a member of the tumor necrosis factor receptor superfamily.7 BDNF has been associated with neuroprotection in ischemic brain injury so, it has prognostic and diagnostic prediction of brain injury.8,9. This evidence concerns the gene BDNF and injury.