After the immunohistochemical analysis on rat aorticvessels, we found that the expression of pro-inflammatory chemokine VAP-1 was higher inthe HHcy + SHR group than the SHR group, suggesting the obvious infiltration ofinflammatory cells in the arterial tissue of hypertension associated with HHcy.Furthermore, we compared the expression levels of inflammatory molecules in rat aortictissues, and found that the inflammatory factor IL-6 and TNF-α, as well as theinflammatory pathway regulator NF-κB p65 and Akt1 were all the highest in the HHcy + SHRgroup. The gene discussed is TNF; the disease is hypertensive disorder.