Inaddition, the immunohistochemical analysis by Image-Pro Plus 6.0 software showed thatthe AO value of VAP-1 was significantly higher in SHR + HHcy group compared to boththe SHR and WKY groups (P < 0.05) (Fig. 3C2),suggesting that HHcy combined with hypertension could significantly increase theinflammatory response in rat arterial wall. This evidence concerns the gene AOC3 and hypertensive disorder.