The FBXO44 protein exhibited significantly higher abundance in S-II AEG tumor samples than in S-II normal samples (P = 1.1E−4, Student’s t test), S-I tumor samples (P = 2.3E−3, Student’s t test), and S-III tumor samples (P = 5.3E−4, Student’s t test) (Fig. 4a). Here, FBXO44 is linked to neoplasm.