Larger scale events included deletions of the 4p, 6p and 17p chromosomal arms, all of which harboured cancer drivers which have been previously linked with EMT, e.g. FGFR3 on 4p37, DAXX and TRIM27 on 6p38,39, TP53 on 17p12 (Supplementary Data 2). This evidence concerns the gene TRIM27 and cancer.