NFKB1 and Sepsis: Post-sepsis bone marrow-derived macrophages and wound macrophages (CD11b+, CD3-, CD19-, Ly6G-) exhibit decreased expression of inflammatory cytokines essential for wound healing (IL-1β, IL-12, and IL-23), which is mediated by reduced expression of MLL1 and decreased H3K4me3 at NFκB binding site on genes related to inflammation [38].