Ethyl, which is a functional group in cannabinol C2 and is similar to Galantamine, can effectively enter the active pocket of AChE [61].Furthermore, THCV consist of Enol as a functional group that might be identified to break up amyloid plaques and enhance the rapid clearance of toxic aggregates in AD which is relatively similar to keto-enol pharmacophores [62]. Here, ACHE is linked to Alzheimer disease.