After adjusting for age, sex, educational levels, income levels, smoking status, alcohol use, physical activity status, hypertension, diabetes mellitus, kidney disease, c-reactive protein, and total energy intake (per 1000 kcal), the result still showed a negative association with depressive scores (β = −0.18, 95% CI −0.34 to −0.02). This evidence concerns the gene CRP and Hypertension.