NLRP3 and amyloidosis: It blocks the NLR family pyrin domain containing 3 (NLRP3) inflammasome and attenuates caspase-1 and IL-1β secretion in mouse models; additionally, it is believed to reduce hypoglycemia-related neuronal apoptosis, increase the number of motor neurons, increase neuronal activity and angiogenesis, and protect neuronal cell cultures from the development of amyloid pathology [9,10,11].