CRP and type 2 diabetes mellitus: A randomized controlled study corroborating these findings, also including T2DM patients, performed some interventions including the supplementation of at least 14,000 IU per week (deficient group: initial supplementation was 50,000 IU per week of vitamin D for three months, and then supplementation was reduced to 14,000 IU per week for another three months), finding a decrease in the concentration of ROS at a follow-up period of 6 months and a decrease in the inflammatory marker CRP, although this was not statistically significant [47].