Using this data, we found that strength training induces significant changes in the expression of 26 genes (10 upregulated: ADCY3, E2F3, JMJD1C, JUND, MLN, MYO1C, PIEZO1, PPARD, SFMBT1, ZNF462; 16 downregulated: CDKAL1, CEP192, DLEU1, GADD45G, GBF1, GLCCI1, MAML3, MMS22L, NYAP2, SDCCAG8, SWT1, TRIB1 WWP2, XPO4, ZBTB38, ZNF420) (Supplementary Table S1), which may partly explain beneficial effects of strength training in the prevention and treatment of sarcopenia. Here, SDCCAG8 is linked to sarcopenia.