CRP and Crohn disease: Treatment is guided by a composite strategy of symptom monitoring through clinical activity indices such as the Pediatric Crohn’s Disease Activity Index (PCDAI)/Crohn’s Disease Activity Index (CDAI) scores and Harvey–Bradshaw Index (HBI), in conjunction with objective measures of inflammation including biochemical markers (fecal calprotectin and C-reactive protein (CRP)), and restaging colonoscopy.