CRP and metabolic syndrome: In 2014, Lee et al. [176] carried out an 8-week, randomized, single-blind, parallel intervention study aiming at comparing the impact of three PUFA-based supplements (corn oil, a botanical oil combination, and fish oil) on the levels of serum fatty acids and other serum lipids (TG and total, HDL-C, and LDL-C), markers of inflammation (leptin and CRP), as well as glucose regulation (glucose and HbA1c) in 59 subjects with early-stage type 2 diabetes or MetS.