GLP1R and polycystic ovary syndrome: In this trial, we found that dulaglutide combined with CRD provided additional benefits respecting HbA1c and PPG as compared with CRD after equivalent weight loss, which was consistent with earlier clinical trial findings showing that GLP-1 RAs could result in significant improvements in HbA1c and post-OGTT glucose levels in women with PCOS [14,36].