In a trial of 192 patients with type 2 diabetes mellitus by Bo et al. [49], resveratrol (40 and 500 mg/d) intervention for 6 months had no significant impact on weight, BMI, blood pressure, glucose, glycated hemoglobin, insulin, uric acid, or interleukin-6 (IL-6). Here, INS is linked to type 2 diabetes mellitus.