A 2017 study by McFarlin et al. found that Bacillus-spore-based probiotic supplementation in participants who exhibited signs of post-prandial dietary endotoxemia resulted in a reduction in several biomarkers of inflammation (IL-12p70, IL-1β, IL-6, IL-8, and MCP-1) [21]. This evidence concerns the gene IL6 and serum lipopolysaccharide activity.