Furthermore, LMP1 also switched glucose metabolism from oxidative phosphorylation to aerobic glycolysis in nasopharyngeal carcinoma cells by promoting DNMT1 mitochondrial translocation, which further led to an increase in the methylation/unmethylation (M/U) ratio of DNA fragments in the mitochondrial DNA D-loop region and a decrease in the DNA levels of MT-COXII, MT-ATP6, and MT-ND6 that encode cytochrome c oxidase subunit II, ATP synthase F0 subunit 6, and NADH dehydrogenase 6, respectively. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.