Furthermore, EVOO-phenols, including OC, reduced oxidative stress and neuroinflammation by targeting nuclear factor erythroid 2–related factor 2 (NRF2), nitric oxide (NO), Janus kinase/signal transducer and activator of transcription (JAK/STAT), and mitogen-activated protein kinase (MAPK) signaling pathways, to list a few, which could synergistically or additively alleviate AD pathology [39,40,41,42,43,44,45,46,47,48]. The gene discussed is SOAT1; the disease is Alzheimer disease.