Moreover, they exerted an inhibitory activity against additional kinases including TRKA and Aurora A. The compound’s activity was confirmed in the murine xenograft model obtained by transplantation of MV4-11 cells by inhibition of the tumor growth rate and in mice inoculated with Ba/F3 expressing FLT3-ITDD835Y by prolongation of animal survival. This evidence concerns the gene FLT3 and neoplasm.