HGF and malignant colon neoplasm: Additionally, both D. maritima bulb extract and ProA express minimal cytotoxic effects against normal HGF when compared to cancer cells (IC50 equals 13.1 μg/mL and 0.229 μg/mL, respectively), indicating that their cytotoxic activities are selective to colon cancer cells, with a very attractive selectivity index of 14.6 for Caco-2 and 5.6 for COLO-205.