It was reported that NQO2 activity contributed to the proliferation of A549 and H1299 cancer cells [13], promoted the establishment of bone metastases of LNCaP-C4-2B prostate cancer [14] and indirectly influenced the activation of NF-kB which resulted in the suppression of cell apoptosis and protection of cancer cells against chemotherapy [15], so NQO2 is considered to be a potential anticancer drug target [16,17,18]. Here, NFKB1 is linked to cancer.