Moreover, studies of the I.29 mouse B cell lymphoma, which undergoes CSR from membrane-bound IgM to IgA, allowed us to characterize transcripts from the unrearranged Cα region in IgM + I.29 cells [102] and to show that the magnitude of Cα GLTs correlates with the efficiency of IgA CSR [103]. This evidence concerns the gene CD40LG and B-cell non-Hodgkin lymphoma.