AKT1 and non-small cell lung carcinoma: Zhao et al. revealed that the activation of mAChRs by pilocarpine can induce a series of biological processes of human non-small cell lung cancer (NSCLC), such as cell proliferation, epithelial-mesenchymal transition (EMT), tumor cell migration and invasion via the MAP kinase, and the Akt pathway [106,107,108].