Additionally, as a very close link to rheumatoid arthritis (RA), Yilmaz et al. [169] and Panezai et al. [170] analyzed CX3CL1 levels in patients with periodontitis and RA, finding a statistically significant increase in their levels compared to their control groups represented by systemically and periodontally healthy patients. This evidence concerns the gene CX3CL1 and periodontitis.