In addition, the prenylated flavonoid from Tephrosia purpurea, glabratephrin, has been shown in recent years to enhance the efficacy of doxorubicin by reducing the affinity of doxorubicin for p-glycoprotein and preventing its efflux without affecting p-glycoprotein expression in triple-negative breast cancer cells [78]. The gene discussed is ABCB1; the disease is triple-negative breast carcinoma.