ALK and anaplastic large cell lymphoma: The researchers use a high-throughput screening experiment to obtain compound 9h, a 3-amino-5-substituted indazole derivative, which shows good inhibitory activity against ALK with an IC50 of 73 nM and also exhibits promising anti-proliferative activity against the ALK-dependent ALCL Karpas-299 cell lines with an IC50 of 253 nM.